Cure OGT
A foundation of Patients, Researchers and Clinicians around the world, joining forces to treat O-GlcNAc Transferase X-Linked Intellectual Disability OGT-XLID
Our Vision:
The Cure OGT Community envisions a world where individuals with OGT-XLID have access to the best possible care, support, and research opportunities.
We strive to create a community of empowered individuals, families, researchers, and clinicians working together to improve the lives of those affected by this rare condition.
Cure OGT at a Glance
OGT-XLID Research Conference 2024
Diagnosed with OGT-XLID?
The OGT Foundation Family Support Network has been created to help families connect and stand united to advance research and resources for OGT-XLID. Register today to join our network and make your voice heard for everyone affected by OGT-XLID.
News, publications and events
OGT Conference 2024 Results
The OGT Conference 2024, held on November 9, brought together leading scientists, clinicians, and families affected by OGT-XLID (OGT-CDG) to discuss the latest advancements in research and explore pathways toward treatment. The event, organized by
The Promise of Emerging AAV Technologies for OGT-XLID Gene Therapy
Gene therapy using adeno-associated viruses (AAVs) has shown significant promise in treating various genetic disorders. However, traditional AAV capsids, such as AAV9, face limitations, especially for larger genes like OGT, the gene implicated in OGT-XLID
OGT Conference 2024: Critical Path to treating OGT-XLID
We are excited to announce OGT Conference 2024, the first-ever event dedicated to OGT-XLIC (also known as OGT-CDG). This landmark conference will bring together leading researchers, clinicians, and families to explore and discuss lates research
Grace Science, LLC Selected by FDA to Participate in the START Pilot Program for GS-100 Gene Therapy for NGLY1 Deficiency and Announcement of the Successful Treatment of the 2nd Patient
Grace Science, LLC Selected by FDA to Participate in the START Pilot Program for GS-100 Gene Therapy for NGLY1 Deficiency and Announcement of the Successful Treatment of the 2nd Patient Grace Science, LLC announced today
New Research Paper: A Novel Mouse Model Sheds Light on OGT-CDG Pathophysiology
Latest work of Daan van Aalten Lab at Molecular Biology & Genetics – Aarhus University by Florence Authier, PhD, Andrew Ferenbach in collaboration with Nina Ondruskova and Alison McNeilly (dundee) on trying to understand the
CAD mutations and uridine-responsive epileptic encephalopathy
Abstract Unexplained global developmental delay and epilepsy in childhood pose a major socioeconomic burden. Progress in defining the molecular bases does not often translate into effective treatment. Notable exceptions include certain inborn errors of metabolism
Our Community:
Patients
Our patients are at the heart of our mission, sharing their experiences to propel research and drive awareness for OGT-XLID.
Researchers
Forward-thinking researchers lead the charge in unraveling the complexities of OGT-XLID and forging new pathways to innovative treatments.
Clinicians
Clinicians familiar with OGT-XLID provide specialized medical knowledge and compassionate care to ensure the best quality of life for our community members.
Get Involved
Your support of the Cure OGT fuels groundbreaking research into OGT-XLID, paving the way for transformative treatments and a healthier future.
Donate
Visit our dedicated Give Lively donation platform by clicking HERE.
Host an event
Fundraisers are a great way to raise OGT-XLID awareness in your community and raise funds for a cause!
Volunteer your time
We need community members and parents willing to become involved with our organization.
Join the Board
We are continually looking for additional individuals willing to serve on our Medical Advisory Board.
Share your story
Inspire other families, researchers and clinicians by sharing a personal story.
Join our community
Help raise awareness of Cure OGT by joining and participating in our activities.